Cannabis and its strains have always been in the news for legal substitutes and variation in the form. THCV is one of the strains: THCV’s intoxicating effects have been debated in the scientific literature for some time. However, the most recent research indicates that it is not a psychoactive cannabinoid. This means that people taking high doses will likely not experience any form of intoxication, and there are no reports to date indicating this effect occurring at lower doses. That being said, there is a lot of uncertainty concerning thcv and thco that entered the market, so you might want to keep on reading for more insight on THCV.
THCV is a chemical compound found in the cannabis plant. It’s similar to THC, which makes up about 10% of its cannabinoid content. Much more research is needed on this cannabinoid to understand how it can affect you when consumed. Also, because of how it sounds, people are often interested in knowing whether or not they will get “high” or intoxicated when using cannabis products containing both THCV and THC (the high producing cannabinoid). THCV is a cannabis compound that exhibits a unique array of effects and medical benefits that are the telltale of its difference from THC and CBD(other compounds found in cannabis and hemp). CBGVA, formed when pyrophosphate reacts with divarinolic acid.
THCV is found in minimal amounts in the cannabis plant and is produced within trichomes. The highest concentrations of THCV can be located near the top of flowering female cannabis plants, while it’s much rarer to find THCV in male cannabis plants or unfertilized female ones (Sikka et al., 1981). THCV has also been found to be present in strains of cannabis that we know produce minimal THC; this is because THCV and THC share the same biosynthetic enzymes (Fellermeier et al., 2001).
The only place to date it is spotted is in cannabis. You can discover THCV in Dagga (Afrikaans for Marijuana), Hash (the resin of the marijuana plant), Wacky baccy (Cannabis sativa containing tobacco and or herbs such as oregano, thyme, etc.), Joints (Marijuana cigarette), King-size, White Widow, Dynamite (a potent strain of cannabis developed in Australia) and many, many other names. THCV is only one of the 450-plus chemical compounds found in Cannabis Sativa.
Is THCV intoxicating? It mainly depends on the individual, their body, their tolerance, and so on. That said, many people use marijuana for medical pain relief, and it’s important to know what you’re getting into when you consume this plant. Some people find that THCV does not affect them at all, while others find that they become high or intoxicated with THCV; meanwhile, others experience no change in their level of intoxication from using cannabis products containing both types of cannabinoids. Suppose you’re considering consuming a product containing both compounds. In that case, it’s worth finding out if your body reacts differently to them than just one cannabinoid before trying any products containing these two substances together.
In the 1970s, some reports indicated that high doses of THCV might cause intoxication in humans. However, it is nearly impossible to reach a high amount of THCV using natural cannabis alone because this compound is present in such small quantities. The reason for this low concentration is that THCV breaks down into CBN when exposed to heat and light, and it is unstable (that is, it degrades relatively quickly) at room temperature. This degradation may also explain the lack of reports on THCV’s intoxicating effects, as previous studies tested THCV administered to humans using cannabis cigarettes containing even more than 100mg of THCV. Doses this high, covering such a wide range of cannabinoids, would have obscured the possible effects of THCV alone.
As stated by this source, it is not a psychoactive cannabinoid. It means that people taking high doses will likely not experience any form of intoxication, and there are no reports to date indicating this effect occurring at lower doses. Since it has been found that THCV breaks down into CBN when the plant is exposed to heat and light, it could make sense that some of the THCV would be lost when cannabis is smoked. On the other hand, CBD may counteract the potentially disorienting effects of THCV by decreasing blood concentrations of THCV. We found in a study that CBD increased concentration levels of THCV in the blood and lowered levels of THCV-COOH. These results indicate that CBD could effectively prevent the onset of paranoid feelings often experienced after smoking some strains high in THCV. Recently we discovered that THCV and CBD work in opposite ways. It seems while THCV can antagonize CB1 receptors, CBD appears to block these actions. It means that the effects of THCV and CBD may depend on whether they share a similar biochemical structure or not; if their designs are identical, then one could counter the other. This finding may help explain the original mystery of THCV, which baffled scientists for decades.
THCV is currently being investigated for its possible use as an anti-obesity agent due to its ability to act as a CB1 antagonist, which reduces appetite and may lead to weight gain. The side effects of THCV are reduced compared with those of THC, given that anxiety and cognitive impairment are less frequently observed in studies on animals.
Studies have demonstrated that the associated side effects of THC were manageable and acceptable for most subjects. In a placebo-controlled study evaluating a standardized cannabis extract with a 20:1 ratio of CBD to THC for the treatment of intractable lower back pain, both the high-dose and low-dose groups experienced significant decreases in pain. However, the effects of CBD appeared to be significantly more pronounced than those of THC at the low dose. The authors hypothesized that the minimal psychoactive properties of CBD, when combined with its efficacy, may have contributed to mood improvement and a reduction in anxiety symptoms.
As mentioned above, a well-documented benefit of CBs is their ability to reduce anxiety. In addition, the CB1 receptor is well known for modulating neurotransmitter release through actions at the presynaptic terminal.
With all your questions answered and doubts cleared, you might want to consider THCV for your pain relief, weight loss, diabetes management. Take advantage of this miraculous herb component that is yet to be banned, if ever, so you don’t miss out on its effects.